Common defenses in homicide cases include self-defense, defense of others, lack of intent, accidental death, mistaken identity, and challenges to witness credibility or forensic reliability. The appropriate defense depends on the specific facts and available evidence. For instance, self-defense requires showing a reasonable belief of imminent harm and proportionate response. In cases focused on identity, demonstrating an alibi or exposing weaknesses in identification procedures can be effective. Each theory requires factual support and often independent investigation to develop evidence that conflicts with the prosecution’s narrative. Defense strategies also include procedural and evidentiary challenges that aim to limit what the jury hears, as well as presenting alternative explanations consistent with innocence or reasonable doubt. Counsel coordinates investigative steps, such as locating witnesses and commissioning forensic testing, to bolster defenses and prepare persuasive courtroom presentations tailored to local jury sensibilities in Lafayette County.